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Cancer Cell Fusion and Post-Hybrid Selection Process (PHSP)

16 Sept 2021

Abstract excerpt

Fusion of cancer cells either with other cancer cells (homotypic fusion) in local vicinity of the tumor tissue or with other cell types (e.g., macrophages, cancer-associated fibroblasts (CAFs), mesenchymal stromal-/stem-like cells (MSC)) (heterotypic fusion) represents a rare event. Accordingly, the clinical relevance of cancer-cell fusion events appears questionable. However, enhanced tumor growth and/or...

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PMID: 34572863
DOI: 10.3390/cancers13184636

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