Article
You complete me: tumor cell-myeloid cell nuclear fusion as a facilitator of organ-specific metastasis
22 Jun 2023
Abstract excerpt
Every cancer genome is unique, resulting in potentially near infinite cancer cell phenotypes and an inability to predict clinical outcomes in most cases. Despite this profound genomic heterogeneity, many cancer types and subtypes display a non-random distribution of metastasis to distant organs, a phenomenon known as organotropism. Proposed factors in metastatic organotropism include hematogenous versus lymphatic...
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