Article

Cancer cell-macrophage fusion increases tumor cell heterogeneity and reshapes their microenvironment

2022-09-19

Abstract excerpt

The trademark of cancer is the ability to evolve, which lays the grounds for progressive events such as metastasis and recurrence. Although genetic mutations and epigenetic changes have been implicated as the mechanisms, they don’t explain why many cancers develop leukocytic traits. Cell fusion between cancer and somatic cells, particularly macrophages, has been suggested as an alternative pathway for cancer cells...

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Literature Corpus work: b58df41b-ab67-5881-b7bb-24251a173182
DOI: 10.21203/rs.3.rs-2062628/v1

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