Article

Associations between epilepsy-related polygenic risk and brain morphology in childhood

2025-01-17

Abstract excerpt

<h4> A bstract </h4> Temporal lobe epilepsy with hippocampal sclerosis (TLE-HS) is associated with a complex genetic architecture, but the translation from genetic risk factors to brain vulnerability remains unclear. Here, we examined associations between epilepsy-related polygenic risk scores for HS (PRS-HS) and brain structure in a large sample of neurotypical children, and correlated these signatures with ca...

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Literature Corpus work: 142fa236-dd7d-5db8-a23c-5047c6002e29
DOI: 10.1101/2025.01.17.633277

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