Article

Brain imaging phenotypes associated with polygenic risk for Essential Tremor

2024-07-16

Abstract excerpt

Essential tremor (ET) is a common movement disorder with a strong genetic basis. Magnetic resonance imaging (MRI), particularly diffusion-weighted MRI (dMRI) and T1 MRI has been used to identify brain abnormalities of ET patients. However, the mechanisms by which genetic risk affects the brain to render individuals vulnerable to ET remain unknown. We aim to understand how ET manifests by identifying presymptomatic...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2c19d3f8-d4d8-55c9-bd9f-0c48dd697942
DOI: 10.1101/2024.07.16.24310501

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Brain imaging phenotypes associated with polygenic risk for Essential TremorDOI 10.1101/2024.07.16.24310501Read

Genome-Wide Meta-Analysis Identifies 47 Novel Loci and Links Essential Tremor to Ventral Diencephalon and Cerebellum MorphometrySemantic proximity Read

Polygenic and spatial insights into the genetic uniqueness of essential tremor using common variants.Semantic proximity Read

Insights into Essential Tremor and Essential Tremor-Plus from Common VariantsSemantic proximity Read

Association of Essential Tremor With Novel Risk Loci: A Genome-Wide Association Study and Meta-analysis.Semantic proximity Read

Essential tremor.Semantic proximity Read

Genome-wide estimates of heritability and genetic correlations in Essential TremorSemantic proximity Read

An Exploratory Analysis of Essential Tremor and Associated PhenotypesSemantic proximity Read

A single-cell eQTL atlas of the human cerebellum reveals vulnerability of oligodendrocytes in essential tremorSemantic proximity Read

An Exploratory Analysis of Essential Tremor and Associated Phenotypes.Semantic proximity Read

Common genetic variation influencing human white matter microstructureSemantic proximity Read

A single-cell eQTL atlas of the human cerebellum reveals vulnerability of oligodendrocytes in essential tremorSemantic proximity Read

Association of polygenic risk for major psychiatric illness with subcortical volumes and white matter integrity in UK Biobank.Semantic proximity Read