Article

Identification and quantification of SARS-CoV-2 leader subgenomic mRNA gene junctions in nasopharyngeal samples shows phasic transcription in animal models of COVID-19 and dysregulation at later time points that can also be identified in humans

2021-03-03

Abstract excerpt

<h4>Introduction</h4> SARS-CoV-2 has a complex strategy for the transcription of viral subgenomic mRNAs (sgmRNAs), which are targets for nucleic acid diagnostics. Each of these sgRNAs has a unique 5’ sequence, the leader-transcriptional regulatory sequence gene junction (leader-TRS-junction), that can be identified using sequencing. <h4>Results</h4> High resolution sequencing has been used to investigate the bio...

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Literature Corpus work: 14229b84-bec8-5c27-930e-309a0f5827ec
DOI: 10.1101/2021.03.03.433753

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Identification and quantification of SARS-CoV-2 leader subgenomic mRNA gene junctions in nasopharyngeal samples shows phasic transcription in animal models of COVID-19 and dysregulation at later time points that can also be identified in humansDOI 10.1101/2021.03.03.433753Read

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