Article

Profiling of SARS-CoV-2 Subgenomic RNAs in Clinical Specimens

2021-12-17

Abstract excerpt

SARS-CoV-2 transcribes a set of subgenomic RNAs (sgRNAs) essential for the translation of structural and accessory proteins to sustain its life cycle. We applied RNA-seq on 375 respiratory samples from individual COVID-19 patients and revealed that the majority of the sgRNAs were canonical transcripts with N being the most abundant (36.2%), followed by S (11.6%), ORF7a (10.3%), M (8.4%), ORF3a (7.9%), ORF8 (6.0%),...

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Literature Corpus work: 226b27da-a130-5c06-a482-860ed31a0147
DOI: 10.2139/ssrn.3987999

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