Article

Altered Subgenomic RNA Expression in SARS-CoV-2 B.1.1.7 Infections

2021-03-03

Abstract excerpt

SARS-CoV-2 lineage B.1.1.7 viruses are more transmissible, may lead to greater clinical severity, and result in modest reductions in antibody neutralization. subgenomic RNA (sgRNA) is produced by discontinuous transcription of the SARS-CoV-2 genome and is a crucial step in the SARS-CoV-2 life cycle. Applying our tool (periscope) to ARTIC Network Oxford Nanopore genomic sequencing data from 4400 SARS-CoV-2 positive...

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Literature Corpus work: 7e894c6c-eeb4-5292-969f-45ef76637665
DOI: 10.1101/2021.03.02.433156

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