Meta-transcriptomic analysis reveals the gene expression and novel conserved sub-genomic RNAs in SARS-CoV-2 and MERS-CoV

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Fundamental to viral biology is identification and annotation of viral genes and their function. Determining the level of coronavirus gene expression is inherently difficult due to the positive stranded RNA genome and the identification of sub-genomic RNAs (sgRNAs) that are required for expression of most viral genes. In the COVID-19 epidemic so far, few genomic studies have...

Topics

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• COVID-19 Clinical Research Studies
• Machine Learning in Bioinformatics
• MicroRNA in disease regulation
• RNA Interference and Gene Delivery
• RNA regulation and disease
• SARS-CoV-2 and COVID-19 Research
• SARS-CoV-2 detection and testing
• Viral gastroenteritis research and epidemiology

Identifiers and source

Literature Corpus work

495d76bd-f5c0-5e5f-9c7e-4fef03efd0e7

DOI

10.1101/2020.04.16.043224