Article

A systematic identification of resistance determinants to antisense antibiotics suggests adaptation strategies dependent on the delivery peptide

2024-10-29

Abstract excerpt

The rise of antimicrobial resistance (AMR) among human pathogenic microbes is a serious threat to global health, calling for the development of novel treatment strategies. Antibiotics based on programmable antisense oligomers (asobiotics) offer an attractive solution to the “arms-race”, as their specificity can be quickly updated and tailored to target resistant bacteria. In order to understand the genetic archite...

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Literature Corpus work: 140e844e-3573-5d2e-84ed-1f62fc9407b7
DOI: 10.1101/2024.10.29.620885

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