Article

An antisense oligomer conjugate with unpredicted bactericidal activity against <i>Fusobacterium nucleatum</i>

2025-02-13

Abstract excerpt

<h4>ABSTRACT</h4> Fusobacteria are commensal members of the oral microbiome that can spread from their primary niche and colonize distal sites in the human body. Their enrichment in colorectal and breast cancer tissue has been associated with tumor growth, metastasis, and chemotherapeutic resistance. The use of non-selective antibiotics to remove fusobacteria impairs tumor progression, but prolonged application r...

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Literature Corpus work: 57f0e0ca-26a2-5f14-8b7a-2f8f38b63dfc
DOI: 10.1101/2025.02.12.637808

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