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Tumour purity as an underlying key factor in tumour mutation detection in colorectal cancer

1 May 2023

Abstract excerpt

The emergence of next-generation sequencing (NGS) technology has enabled the large-scale identification of personalised genetic characteristics of colorectal cancer (CRC).1 However, the accuracy may be influenced by certain sample factors, such as sampling methods, biospecimen type (fresh vs. formalin-fixed paraffin-embedded) and input DNA amount.2-4 We creatively performed a contrastive analysis based on...

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PMID: 37132162
DOI: 10.1002/ctm2.1252

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