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Low tumor purity is associated with poor prognosis, heavy mutation burden, and intense immune phenotype in colon cancer

1 Sept 2018

Abstract excerpt

Purpose: Tumor purity is defined as the proportion of cancer cells in the tumor tissue. The impact of tumor purity on colon cancer (CC) prognosis, genetic profile, and microenvironment has not been thoroughly accessed. Materials and methods: Clinical and transcriptomic data from three public datasets, GSE17536/17537, GSE39582, and TCGA, were retrospectively collected (n=1,248). Tumor purity of each sample was...

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PMID: 30271205
DOI: 10.2147/cmar.s171855

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