Article

The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype

2022-04-28

Abstract excerpt

Variant of concern (VOC) Omicron-BA1 has achieved global predominance in early 2022. Therefore, surveillance and comprehensive characterization of Omicron-BA.1 in advanced primary cell culture systems and multiple animal models is urgently needed. Here, we characterized Omicron-BA.1 and recombinant Omicron-BA.1 spike gene mutants in comparison with VOC Delta in well-differentiated primary human nasal and bronchial...

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Literature Corpus work: 13f9e044-6198-513a-8806-d93e1fb29268
DOI: 10.1101/2022.04.28.489537

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