Multiple mutations of SARS-CoV-2 Omicron BA.2 variant orchestrate its virological characteristics.

doi:10.1128/jvi.01011-23

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Article

Multiple mutations of SARS-CoV-2 Omicron BA.2 variant orchestrate its virological characteristics.

Journal of virology - 31 Oct 2023

Kimura Izumi, Yamasoba Daichi, Nasser Hesham, Ito Hayato, Zahradnik Jiri, Wu Jiaqi, Fujita Shigeru, Uriu Keiya, Sasaki Jiei, Tamura Tomokazu, Suzuki Rigel, Deguchi Sayaka, Plianchaisuk Arnon, Yoshimatsu Kumiko, Kazuma Yasuhiro, Mitoma Shuya, Schreiber Gideon, Asakura Hiroyuki, Nagashima Mami, Sadamasu Kenji, Yoshimura Kazuhisa, Takaori-Kondo Akifumi, Ito Jumpei, Shirakawa Kotaro, Takayama Kazuo, Irie Takashi, Hashiguchi Takao, Nakagawa So, Fukuhara Takasuke, Saito Akatsuki, Ikeda Terumasa, Sato Kei

Abstract excerpt

IMPORTANCE: Most studies investigating the characteristics of emerging SARS-CoV-2 variants have been focusing on mutations in the spike proteins that affect viral infectivity, fusogenicity, and pathogenicity. However, few studies have addressed how naturally occurring mutations in the non-spike regions of the SARS-CoV-2 genome impact virological properties. In this study, we proved that multiple SARS-CoV-2...

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PMID: 37796123
DOI: 10.1128/jvi.01011-23
PMCID: PMC10781145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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