Article
Phenotypic evolution of SARS-CoV-2 spike during the COVID-19 pandemic
3 Jan 2025
Abstract excerpt
SARS-CoV-2 variants are mainly defined by mutations in their spike. It is therefore critical to understand how the evolutionary trajectories of spike affect virus phenotypes. So far, it has been challenging to comprehensively compare the many spikes that emerged during the pandemic in a single experimental platform. Here we generated a panel of recombinant viruses carrying different spike proteins from 27...
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