Article

Analysis of whole exome sequencing in severe mental illness hints at selection of brain development and immune related genes

2021-05-12

Abstract excerpt

Evolutionary trends may underlie some aspects of the risk for common, non-communicable disorders, including psychiatric disease. We analyzed whole exome sequencing data from 80 unique individuals from India coming from families with two or more individuals with severe mental illness. We used Population Branch Statistics (PBS) to identify variants and genes under positive selection and identified 75 genes as candid...

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Literature Corpus work: 13f05e81-1fb7-5e21-a550-b9ccd4aa84b8
DOI: 10.1101/2021.05.11.21257013

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