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Article

Genetic variations in evolutionary accelerated regions disrupt cognition in schizophrenia.

Psychiatry research - 1 Aug 2022

Bhattacharyya Upasana, Bhatia Triptish, Deshpande Smita N, Thelma B K

Abstract excerpt

Cognition is believed to be a product of human evolution, while schizophrenia is ascribed as the by-product with cognitive impairment as it's genetically mediated endophenotype. Genomic loci associated with these traits are enriched with recent evolutionary markers such as Human accelerated regions (HARs). HARs are markedly different in humans since their divergence with chimpanzees and mostly regulate gene...

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Identifiers

PMID: 35623238
DOI: 10.1016/j.psychres.2022.114586
PMCID: PMC10150587

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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