Article

Genetic Variations in Evolutionary Accelerated Regions Disrupt Cognition in Schizophrenia

2021-02-26

Abstract excerpt

Cognition is believed to be a product of human evolution, while schizophrenia is ascribed as the by-product with cognitive impairment as it’s genetically mediated endophenotype. Genomic loci associated with these traits are enriched with recent evolutionary markers such as Human accelerated regions (HARs). HARs are markedly different in humans since their divergence with chimpanzees and mostly regulate gene expres...

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Literature Corpus work: 537a56c6-78a1-5493-a024-d6a8b77b32c8
DOI: 10.1101/2021.02.24.21252224

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