Article

The influence of calcific aortic stenosis on atrioventricular conduction: a prospective observational study and Mendelian randomization

2024-05-10

Abstract excerpt

<h4>Background</h4> Aortic stenosis (AS) may prolong atrioventricular (AV) conduction secondary to calcium infiltration of the atrioventricular-His-pathway, which is hypothesized to contribute to bradyarrhythmia and sudden cardiac death in this cohort. This study investigates the correlation between calcific AS and impaired AV conduction. <h4>Methods</h4> We performed an observational study and Mendelian randomiza...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 13d8f8b0-eb64-5b71-9385-ca1aeffb3629
DOI: 10.1101/2024.05.08.24307094

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The influence of calcific aortic stenosis on atrioventricular conduction: a prospective observational study and Mendelian randomizationDOI 10.1101/2024.05.08.24307094Read

Digital phenotyping of aortic stenosis-related remodeling reveals complementary structural, electrical, and hemodynamic signaturesSemantic proximity Read

Genetics of Calcific Aortic Stenosis: A Systematic Review.Semantic proximity Read

Calcific Aortic Valve Disease: Part 1--Molecular Pathogenetic Aspects, Hemodynamics, and Adaptive Feedbacks.Semantic proximity Read

Effect of Glucagon-like Peptide-1 Receptor Agonism on Aortic Valve Stenosis Risk: A Mendelian Randomization AnalysisSemantic proximity Read

Observational and Genetic Associations of Modifiable Risk Factors with Aortic Valve Stenosis: A Prospective Cohort Study of 0.5 Million ParticipantsSemantic proximity Read

Calcium Signaling Pathway Genes RUNX2 and CACNA1C Are Associated With Calcific Aortic Valve Disease.Semantic proximity Read

Systolic Blood Pressure and Risk of Valvular Heart DiseaseSemantic proximity Read

Distinct Genetic Risk Profile in Aortic Stenosis Compared With Coronary Artery Disease.Semantic proximity Read

Benefits of Better Cardiovascular Health for Calcific Aortic Valve Stenosis Stratified by Polygenic Risk Score.Semantic proximity Read

Dyslipidemia, inflammation, calcification, and adiposity in aortic stenosis: a genome-wide study.Semantic proximity Read

Epigenetic age acceleration and risk of aortic valve stenosis: a bidirectional Mendelian randomization studySemantic proximity Read

Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction.Semantic proximity Read