Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Calcific Aortic Valve Disease: Part 1--Molecular Pathogenetic Aspects, Hemodynamics, and Adaptive Feedbacks.

Journal of cardiovascular translational research - 1 Apr 2016

Pasipoularides Ares

Abstract excerpt

Aortic valvular stenosis (AVS), produced by calcific aortic valve disease (CAVD) causing reduced cusp opening, afflicts mostly older persons eventually requiring valve replacement. CAVD had been considered "degenerative," but newer investigations implicate active mechanisms similar to atherogenesis--genetic predisposition and signaling pathways, lipoprotein deposits, chronic inflammation, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aortic Valve
Share to Aortic Valve Stenosis
Share to Calcinosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Feedback, Physiological

Share to Hemodynamics

Share to Mechanotransduction, Cellular

Share to Predictive Value of Tests

Share to Ventricular Function, Left

Source

Open in PubMed Open full text

Identifiers

PMID: 26891845
DOI: 10.1007/s12265-016-9679-z
PMCID: PMC4833551

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Calcific Aortic Valve Disease: Part 1--Molecular Pathogenetic Aspects, Hemodynamics, and Adaptive Feedbacks.PMID 26891845Read ↗

Calcific Aortic Valve Disease: Part 2-Morphomechanical Abnormalities, Gene Reexpression, and Gender Effects on Ventricular Hypertrophy and Its Reversibility.Semantic proximity Read ↗

The Complex Interplay of Inflammation, Metabolism, Epigenetics, and Sex in Calcific Disease of the Aortic ValveSemantic proximity Read ↗

Insights into degenerative aortic valve disease.Semantic proximity Read ↗

Nonrheumatic calcific aortic stenosis: an overview from basic science to pharmacological prevention.Semantic proximity Read ↗

Genomics: the next step to elucidate the etiology of calcific aortic valve stenosis.Semantic proximity Read ↗

The Complex Relationship between Hypoxia Signaling, Mitochondrial Dysfunction and Inflammation in Calcific Aortic Valve Disease: Insights from the Molecular Mechanisms to Therapeutic ApproachesSemantic proximity Read ↗

Sex-Specific Features of Calcific Aortic Valve Disease.Semantic proximity Read ↗

Multi-Omics Approaches to Define Calcific Aortic Valve Disease Pathogenesis.Semantic proximity Read ↗

The progression of calcific aortic valve disease through injury, cell dysfunction, and disruptive biologic and physical force feedback loops.Semantic proximity Read ↗

Mechanisms of aortic valve calcification.Semantic proximity Read ↗

Calcific Aortic Valve Stenosis and Atherosclerotic Calcification.Semantic proximity Read ↗

[Gene polymorphisms leading to calcified and stenotic aortic valves].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.