Article
Distinct Genetic Risk Profile in Aortic Stenosis Compared With Coronary Artery Disease.
JAMA cardiology - 1 Feb 2025
Trenkwalder Teresa, Maj Carlo, Al-Kassou Baravan, Debiec Radoslaw, Doppler Stefanie A, Musameh Muntaser D, Nelson Christopher P, Dasmeh Pouria, Grover Sandeep, Knoll Katharina, Naamanka Joonas, Mordi Ify R, Braund Peter S, Dreßen Martina, Lahm Harald, Wirth Felix, Baldus Stephan, Kelm Malte, von Scheidt Moritz, Krefting Johannes, Ellinghaus David, Small Aeron M, Peloso Gina M, Natarajan Pradeep, Thanassoulis George, Engert James C, Dufresne Line, Franke Andre, Görg Siegfried, Laudes Matthias, Nowak-Göttl Ulrike, Vaht Mariliis, Metspalu Andres, Stoll Monika, Berger Klaus, Pellegrini Costanza, Kastrati Adnan, Hengstenberg Christian, Lang Chim C, Kessler Thorsten, Hovatta Iiris, Nickenig Georg, Nöthen Markus M, Krane Markus, Schunkert Heribert, Samani Nilesh J, Schumacher Johannes, Kals Mart, Reigo Anu, Teder-Laving Maris, Gehlen Jan, Webb Thomas R, Giel Ann-Sophie, Koebbe Laura L, Feirer Nina, Billmann Maximilian, Srinivasan Sundar, Zimmer Sebastian, Palmer Colin N A, Li Ling, Yang Chuhua, Borisov Oleg, Adam Matti, Veulemans Verena, Joner Michael, Xhepa Erion
Abstract excerpt
Importance: Aortic stenosis (AS) and coronary artery disease (CAD) frequently coexist. However, it is unknown which genetic and cardiovascular risk factors might be AS-specific and which could be shared between AS and CAD. Objective: To identify genetic risk loci and cardiovascular risk factors with AS-specific associations. Design, Setting, and Participants: This was a genomewide association study (GWAS) of AS...
Topics
Join the communities discussing this publication.