Article
Detection of microRNA SNPs with ultrahigh specificity by using reduced graphene oxide-assisted rolling circle amplification.
Chemical communications (Cambridge, England) - 21 Jun 2015
Zhu Xiaoli, Shen Yalan, Cao Jiepei, Yin Li, Ban Fangfang, Shu Yongqian, Li Genxi
Abstract excerpt
Here we report a reduced graphene oxide-assisted rolling circle amplification for the detection of miRNA SNPs. The difference of the signal of a miRNA SNP reaches 100 fold, a value over 10 times larger than some current methodologies, which allows the discrimination of a SNP even with the naked eye.
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