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The <i>C. elegans</i> homolog of the <i>Evi1</i> proto-oncogene, <i>egl-43</i> , coordinates G1 cell cycle arrest with pro-invasive gene expression during anchor cell invasion

2019-10-11

Abstract excerpt

Cell invasion allows cells to migrate across compartment boundaries formed by basement membranes. Aberrant cell invasion is a first step during the formation of metastases by malignant cancer cells. Anchor cell (AC) invasion in C. elegans is an excellent in vivo model to study the regulation of cell invasion during development. Here, we have examined the function of egl-43 , the homolog of the human Evi1 proto...

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Literature Corpus work
13b73b8a-3684-5a58-b8e2-7d7659faa2a4
DOI
10.1101/802355
Open publication

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The <i>C. elegans</i> homolog of the <i>Evi1</i> proto-oncogene, <i>egl-43</i> , coordinates G1 cell cycle arrest with pro-invasive gene expression during anchor cell invasionDOI 10.1101/802355
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