Article

Entropy of a bacterial stress response is a generalizable predictor for fitness and antibiotic sensitivity

2019-10-22

Abstract excerpt

Genes implicated in bacterial stress responses have been used to construct models that infer the growth outcome of a bacterium in the presence of antibiotics with the objective to develop novel diagnostic methods in the clinic. Current models are trained on data specific to a species or type of stress, making them potentially limited in their application. It is unclear if a generalizable response-signature exists...

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Identifiers and source

Literature Corpus work: 1398b916-3f43-557c-be2e-d818a37537ee
DOI: 10.1101/813709

Open publication

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