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Article

A fine scale phenotype-genotype virulence map of a bacterial pathogen.

Genome research - 1 Dec 2012

van Opijnen Tim, Camilli Andrew

Abstract excerpt

A large fraction of the genes from sequenced organisms are of unknown function. This limits biological insight, and for pathogenic microorganisms hampers the development of new approaches to battle infections. There is thus a great need for novel strategies that link genotypes to phenotypes for microorganisms. We describe a high-throughput strategy based on the method Tn-seq that can be applied to any genetically...

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Identifiers

PMID: 22826510
DOI: 10.1101/gr.137430.112
PMCID: PMC3514683

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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