Article

Revealing Transcriptomic Responses in <i>Escherichia coli</i> During Early Antibiotic Exposure

2025-09-20

Abstract excerpt

The earliest responses of pathogenic bacteria to antibiotics can affect the outcome of an infection. While long-term adaptations have been extensively studied, the immediate transcriptional changes that unfold immediately following antibiotic exposure remain poorly understood. Here, we applied iModulon analysis to time-resolved transcriptomic data from Escherichia coli exposed to subinhibitory concentrations of t...

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Literature Corpus work: 98f2ac27-ec3c-585a-abfa-f880aad020eb
DOI: 10.1101/2025.09.17.676618

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