Article

Genomic Profiling of lower-grade gliomas subtype with distinct molecular and clinicopathologic characteristics via altered DNA-damage repair features

2023-02-16

Abstract excerpt

<title>Abstract</title> <p> Lower WHO grade II and III gliomas (LGGs) are characterized by widespread genetic and transcriptional heterogeneity, yet little is known about the heterogeneity of the DNA Damage Repair (DDR), its function in tumor biology, coupling with the transcriptome and tumor microenvironment (TM) and its possible impact for tumor development. In this study, the DNA damage repair (DDR) alteratio...

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Literature Corpus work: 13962371-9053-5b00-b383-e5b3b29a1431
DOI: 10.21203/rs.3.rs-2105584/v2

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