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Article

Integrative analyses identify a DNA damage repair gene signature for prognosis prediction in lower grade gliomas.

Future oncology (London, England) - 1 Mar 2020

Pang Feng-Mei, Yan Han, Mo Jun-Luan, Li Dan, Chen Yi, Zhang Longbo, Liu Zhao-Qian, Zhou Hong-Hao, Wu Jun, Li Xi

Abstract excerpt

Background: The DNA damage repair (DDR) pathways play important roles for regulating cancer progression and therapeutic response. IDH mutations, well-known prognosis biomarkers for glioma, lead to hypermethylation of tumor cells and affect genes' expression. Whether IDH mutations affect glioma prognosis through influencing the expression of DDR genes remains unclear. Methods: A total of 272 DDR genes were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32065545
DOI: 10.2217/fon-2019-0764

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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