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Article

Molecular and clinical characterization of IDH associated immune signature in lower-grade gliomas

1 Feb 2018

Abstract excerpt

Background: Mutations in isocitrate dehydrogenase (IDH) affect the development and prognosis of gliomas. We investigated the role of IDH mutations in the regulation of immune phenotype in lower-grade gliomas (LGGs).Method and patients: A total of 1,008 cases with clinical and IDH mutation data from five cohorts were enrolled. Samples with RNA sequencing data from the Chinese Glioma Genome Atlas (CGGA) were used...

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Identifiers

PMID: 29872572
DOI: 10.1080/2162402x.2018.1434466

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