Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel DNA damage and repair-related gene signature to improve predictive capacity of overall survival for patients with gliomas.

Journal of cellular and molecular medicine - 1 Jul 2022

Li Xiaodong, Wang Yichang, Wu Wei, Xiang Jianyang, Wang Maode, Yu Hai

Abstract excerpt

Gliomas, as the most lethal and malignant brain tumours in adults, remain a major challenge worldwide. DNA damage and repair-related genes (DDRRGs) appear to play a significant role in gliomas, but the studies of DDRRGs are still insufficient. Herein, we systematically explored and analysed 1547 DDRRGs in 938 glioma samples from TCGA and CGGA datasets. Using least absolute shrinkage and selection operator (LASSO)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Brain Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosome Aberrations

Share to DNA Damage

Share to Glioma

Share to Glioma Diagnosis and Treatment

Share to Isocitrate Dehydrogenase

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 35615996
DOI: 10.1111/jcmm.17406
PMCID: PMC9258707

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel DNA damage and repair-related gene signature to improve predictive capacity of overall survival for patients with gliomas.PMID 35615996Read ↗

A Prognostic DNA Damage Repair Genes Signature and Its Impact on Immune Cell Infiltration in GliomaSemantic proximity Read ↗

Genomic Profiling of lower-grade gliomas subtype with distinct molecular and clinicopathologic characteristics via altered DNA-damage repair featuresSemantic proximity Read ↗

A multi-omics analysis-based model to predict the prognosis of low-grade gliomas.Semantic proximity Read ↗

Identification of an epigenetic prognostic signature for patients with lower‐grade gliomasSemantic proximity Read ↗

A gene signature predicting prognosis of patients with low- grade gliomas receiving temozolomide therapySemantic proximity Read ↗

Identification of a three-long non-coding RNA signature for predicting survival of temozolomide-treated isocitrate dehydrogenase mutant low-grade gliomas.Semantic proximity Read ↗

Comprehensive analysis of m6A/m5C/m1A-related gene expression, immune infiltration, and sensitivity of antineoplastic drugs in gliomaSemantic proximity Read ↗

Development of An Inflammatory Response-Related Gene Signature To Predict Prognosis and Immunotherapy Response For Patients With GliomaSemantic proximity Read ↗

M2 TAM-related risk signature based on single-cell and bulk RNA sequencing to evaluate tumor immune microenvironment and predict prognosis in gliomaSemantic proximity Read ↗

Identification and Validation of RNA Methylation-Related Related Alternative Splicing Gene Signature for Low Grade Glioma to Predict Survival and Immune LandscapesSemantic proximity Read ↗

Molecular subtyping of glioblastoma based on immune-related genes for prognosisSemantic proximity Read ↗

Identification of a Novel Disulfideptosis-Related LncRNA Signature and Integrative Analyses in Patients with GliomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.