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Article

Comparative genomic landscape of lower-grade glioma and glioblastoma.

PloS one - 1 Jan 2024

Sun Xinxin, Jia Qingbin, Li Kun, Tian Conghui, Yi Lili, Yan Lili, Zheng Juan, Jia Xiaodong, Gu Mingliang

Abstract excerpt

Biomarkers for classifying and grading gliomas have been extensively explored, whereas populations in public databases were mostly Western/European. Based on public databases cannot accurately represent Chinese population. To identify molecular characteristics associated with clinical outcomes of lower-grade glioma (LGG) and glioblastoma (GBM) in the Chinese population, we performed whole-exome sequencing (WES)...

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PMID: 39208202
DOI: 10.1371/journal.pone.0309536
PMCID: PMC11361568

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