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RFC2: a prognosis biomarker correlated with the immune signature in diffuse lower-grade gliomas

24 Feb 2022

Abstract excerpt

Diffuse lower-grade gliomas (LGG) represent the highly heterogeneous and infiltrative neoplasms in the central nervous system (CNS). Replication factor C 2 (RFC2) is a subunit of the RFC complex that modulates DNA replication and repair. However, the prognosis value of RFC2 and its association with the immune signature of tumor microenvironment (TME) in LGG remains unknown. Based on Oncomine, TCGA, GTEx, TIMER,...

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PMID: 35210438
DOI: 10.1038/s41598-022-06197-5

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