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Analysis of RNA/DNA Hybrid Profiles in Blood From Autistic Patients Reveals Differences in mRNA and non-coding RNA Regions

2024-10-18

Abstract excerpt

DNA/RNA hybrids are present in normal cellular physiology, but when misregulated in the genome, they can contribute to human pathologies such as neurodevelopmental disorders and cancer. These hybrid structures are often abundant in repetitive genomic sequences such as telomeres and centromeres, contributing to evolutionary conserved phenomena. However, excessive accumulation can lead to DNA damage and genomic inst...

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Literature Corpus work
1366f4c8-f388-5092-9a09-9b602505a7a7
DOI
10.1101/2024.10.18.618986
Open publication

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Analysis of RNA/DNA Hybrid Profiles in Blood From Autistic Patients Reveals Differences in mRNA and non-coding RNA RegionsDOI 10.1101/2024.10.18.618986
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