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Article

Transcriptional Gene Silencing of the Autism-Associated Long Noncoding RNA MSNP1AS in Human Neural Progenitor Cells.

Developmental neuroscience - 1 Jan 2016

DeWitt Jessica J, Hecht Patrick M, Grepo Nicole, Wilkinson Brent, Evgrafov Oleg V, Morris Kevin V, Knowles James A, Campbell Daniel B

Abstract excerpt

The long noncoding RNA MSNP1AS (moesin pseudogene 1, antisense) is a functional element that was previously associated with autism spectrum disorder (ASD) with genome-wide significance. Expression of MSNP1AS was increased 12-fold in the cerebral cortex of individuals with ASD and 22-fold in individuals with a genome-wide significantly associated ASD genetic marker on chromosome 5p14.1. Overexpression of MSNP1AS...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28030860
DOI: 10.1159/000453258
PMCID: PMC5759311

Genes

OAS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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