Article

Phosphatidic Acid Mediated Sonodynamic Therapy Facilitates M1 Macrophage Osteoclastic Function and Alleviates Early Vascular Calcification

2024-10-11

Abstract excerpt

<h4>BACKGROUND</h4> Vascular calcification significantly influences the onset and outcome of cardiovascular events, yet no effective treatment currently exists. Dysfunction of osteoclastic macrophages contributes to the formation of calcification. Our previous studies have shown that sonodynamic therapy (SDT) can rapidly reverse atherosclerotic plaques by targeting macrophages. This study aimed to investigate the...

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Literature Corpus work: 130dc69d-9a1b-5eae-a324-2ba53eded7fa
DOI: 10.1101/2024.10.10.24315275

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