Article

Novel treatment of small and large artery calcific disease via epigenetic activation of autophagy initiation genes

2022-05-03

Abstract excerpt

<title>Abstract</title> <p>Vascular calcification is a hallmark of atherosclerotic disease and serves as a strong predictor and risk factor for cardiovascular events1. Growing evidence points towards macroautophagy (herein referred to simply as autophagy), a cellular self-degradation process, as being protective during early atherosclerosis2. However, autophagy may become dysregulated with advanced atherosclerosi...

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Literature Corpus work: 2561cee1-515d-5ec6-ad61-0ce3ae626cb8
DOI: 10.21203/rs.3.rs-1602008/v1

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