Article

Inverse association between coronary artery calcification and plasma pyrophosphate: systemic deficiency and local compensation

2025-08-24

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Plasma inorganic pyrophosphate (PPi) is a potent endogenous inhibitor of vascular calcification, but its clinical relevance in coronary artery calcification (CAC) has not yet been established. <h4>Objectives</h4> This study investigates the association between plasma PPi levels and coronary artery calcification, alongside potential local vascular compensatory mechanisms. <h...

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Literature Corpus work: 0ea49787-cdd3-540b-bfef-9ce4b085b0dc
DOI: 10.1101/2025.08.21.25334157

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