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Ex vivo culture to evaluate dynamic changes in the tumor microenvironment following durvalumab treatment

2025-08-08

Abstract excerpt

<title>Abstract</title> <p>While the tumor microenvironment (TME) is critical to the mechanism of action of anti-PD-1/PD-L1 checkpoint inhibitions, limitations exist to understand this using in vitro and in vivo models. With bladder (BCa) and prostate (PCa) cancer representing cancer with respectively strong and poor responses to PD-1/PD-L1 inhibition, we used ex vivo culture of fresh patient cancer tissue to bet...

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Literature Corpus work
130d93f5-5b8e-5130-ad0a-cbec7bb3376c
DOI
10.21203/rs.3.rs-7180379/v1
Open publication

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Ex vivo culture to evaluate dynamic changes in the tumor microenvironment following durvalumab treatmentDOI 10.21203/rs.3.rs-7180379/v1
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