Article

Phosphoproteomics identifies the DYRK1B protein kinase as a regulator of processing bodies

2026-05-01

Abstract excerpt

<h4>ABSTRACT</h4> Dual-specificity tyrosine-phosphorylation-regulated kinase 1B (DYRK1B) modulates the cell cycle, cell fate during development, and is deregulated in cancer and metabolic syndrome. However, only a few DYRK1B substrates have been defined, so we undertook a phosphoproteomics screen in cells that exhibit inducible DYRK1B expression. Motif analysis revealed enrichment for proline-directed serine or t...

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Literature Corpus work: 1305f47f-9940-530f-8a36-7642769b3f8a
DOI: 10.64898/2026.04.29.721300

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