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Virus Infection Variability by Single-Cell Profiling

9 Aug 2021

Abstract excerpt

Cell-to-cell variability of infection has long been known, yet it has remained one of the least understood phenomena in infection research. It impacts on disease onset and development, yet only recently underlying mechanisms have been studied in clonal cell cultures by single-virion immunofluorescence microscopy and flow cytometry. In this review, we showcase how single-cell RNA sequencing (scRNA-seq),...

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PMID: 34452433
DOI: 10.3390/v13081568

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