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Article

Comparison of gene set scoring methods for reproducible evaluation of multiple tuberculosis gene signatures

2023-01-20

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Rationale</h4> Many blood-based transcriptional gene signatures for tuberculosis (TB) have been developed with potential use to diagnose disease, predict risk of progression from infection to disease, and monitor TB treatment outcomes. However, an unresolved issue is whether gene set enrichment analysis (GSEA) of the signature transcripts alone is sufficient for prediction and differentiati...

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Literature Corpus work
12f89ea1-212c-5bd2-b734-be827d0abb93
DOI
10.1101/2023.01.19.520627
Open publication

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Comparison of gene set scoring methods for reproducible evaluation of multiple tuberculosis gene signaturesDOI 10.1101/2023.01.19.520627
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