Article

Common gene signature model discovery and systematic validation for TB prognosis and response to treatment

2022-11-30

Abstract excerpt

<h4>ABSTRACT</h4> While blood gene signatures have shown promise in tuberculosis (TB) diagnosis and treatment monitoring, most signatures derived from a single cohort may be insufficient to capture TB heterogeneity in populations and individuals. Here we report a new generalized approach combining a network-based meta-analysis with machine-learning modeling to leverage the power of heterogeneity among studies. Th...

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Literature Corpus work: 79008b7d-cf0e-50cc-8279-c0420012b0ec
DOI: 10.1101/2022.11.28.518302

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