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Combining blood transcriptomic signatures improves the prediction of progression to tuberculosis among household contacts in Brazil

2025-09-21

Abstract excerpt

<h4>ABSTRACT</h4> Tuberculosis remains a major health threat, infecting nearly a third of the world’s population. Of those infected, 5-10% progress from latent infection to active tuberculosis (TB) disease and biomarkers to identify which individuals will progress are needed to allow targeted prophylactic treatment. Several risk biomarkers have been developed to predict progression but have not been tested head-t...

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Literature Corpus work
ca11f858-a142-5a8e-8c98-1025e601a8fb
DOI
10.1101/2025.09.19.25336212
Open publication

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Combining blood transcriptomic signatures improves the prediction of progression to tuberculosis among household contacts in BrazilDOI 10.1101/2025.09.19.25336212
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