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Article

Bidirectional Crosstalk Between Cancer Stem Cells and Immune Cell Subsets.

Frontiers in immunology - 1 Jan 2020

Müller Luise, Tunger Antje, Plesca Ioana, Wehner Rebekka, Temme Achim, Westphal Dana, Meier Friedegund, Bachmann Michael, Schmitz Marc

Abstract excerpt

Cancer stem cells (CSCs), also known as tumor-initiating cells, are characterized by an increased capacity for self-renewal, multipotency, and tumor initiation. While CSCs represent only a small proportion of the tumor mass, they significantly account for metastatic dissemination and tumor recurrence, thus making them attractive targets for therapy. Due to their ability to sustain in dormancy, chemo- and...

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Source

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Identifiers

PMID: 32117287
DOI: 10.3389/fimmu.2020.00140
PMCID: PMC7013084

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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