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Clinically Translatable Approaches of Inhibiting TGF-β to Target Cancer Stem Cells in TNBC

2021-09-08

Abstract excerpt

Triple-negative breast cancer (TNBC) is a subtype of breast cancer that disproportionally accounts for the majority of breast cancer-related deaths due to the lack of specific targets for effective treatments. In this review, we highlight the complexity of the transforming growth factor-beta family (TGF-β) pathway and discuss how the dysregulation of the TGF-β pathway promotes oncogenic attributes in TNB...

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Literature Corpus work
92bb95b9-b96e-5109-8d12-b1aa186ce570
DOI
10.20944/preprints202109.0047.v2
Open publication

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