Article

Melanoma-secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis

2019-11-26

Abstract excerpt

<h4>Summary</h4> Brain metastasis is a significant cause of morbidity and mortality in multiple cancer types and represents an unmet clinical need. The mechanisms that mediate metastatic cancer growth in the brain parenchyma are largely unknown. Melanoma, which has the highest rate of brain metastasis among common cancer types, is an ideal model to study how cancer cells adapt to the brain parenchyma. We performe...

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Literature Corpus work: 12740fde-98a7-538d-a53c-2b50231cd3d8
DOI: 10.1101/854885

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