Melanoma brain colonization involves the emergence of a brain-adaptive phenotype

Abstract excerpt

The brain offers a unique microenvironment that plays an important role in the establishment and progression of metastasis. However, the molecular determinants that promote development of melanoma brain metastases are largely unknown. Utilizing two species of immune-compromised animals, with in vivo cultivated metastatic tissues along with their corresponding host tissues in a metastasis model, we here identify...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cancer, Stress, Anesthesia, and Immune Response
• Share to Nicotinic Acetylcholine Receptors Study
• Share to Receptor Mechanisms and Signaling