Article

Distinct tumor architectures for metastatic colonization of the brain

2023-01-31

Abstract excerpt

<h4>Summary</h4> Brain metastasis is a dismal cancer complication, hinging on the initial survival and outgrowth of disseminated cancer cells. To understand these crucial early stages of colonization, we investigated two prevalent sources of cerebral relapse, triple-negative (TNBC) and HER2+ breast cancer (HER2BC). We show that these tumor types colonize the brain aggressively, yet with distinct tumor architectur...

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Literature Corpus work: 24ca4bef-7e78-59a8-8abe-397d57ac4faa
DOI: 10.1101/2023.01.27.525190

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