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TelNet - a database for human and yeast genes involved in telomere maintenance

18 May 2018

Abstract excerpt

BACKGROUND: The ends of linear chromosomes, the telomeres, comprise repetitive DNA sequences in complex with proteins that protects them from being processed by the DNA repair machinery. Cancer cells need to counteract the shortening of telomere repeats during replication for their unlimited proliferation by reactivating the reverse transcriptase telomerase or by using the alternative lengthening of telomeres...

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Share to Telomeres, Telomerase, and Senescence
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PMID: 29776332
DOI: 10.1186/s12863-018-0617-8

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